Schizophrenia: A New Approach. II. Result of a Year's Research
Journal of Mental Science January 1, 1954 A. Hoffer, H Osmond, John Smythies 300 citations
A hypothesis that a substance with properties between mescaline and adrenaline, called M substance, might be an aetiological agent in schizophrenia was proposed a year earlier. The current paper reports on a year of collaborative testing of that hypothesis. The hypothesis suggested that such a substance, with mescaline-like psychological effects but adrenaline-like concentrations, could account for schizophrenia better than existing theories.