Methylenedioxyamphetamine
Archives of Internal Medicine October 1, 1981 Dennis L. Simpson 36 citations
Methylenedioxyamphetamine, a street drug structurally similar to both mescaline and amphetamine, can cause severe and fatal toxicity, contrary to its reputation as a mild hallucinogen. A patient experienced sympathomimetic effects, coma, seizures, hyperreflexia, and hyperthermia. After initial stabilization, the condition deteriorated with uncontrollable hyperthermia, hematologic abnormalities, and coma leading to death. Because hyperthermia involves both central and peripheral mechanisms, phentolamine mesylate may be the preferred treatment in future cases.