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George B. Koelle

University of Pennsylvania

1 paper in the library · 18 citations · publishing 1958

Papers

The Pharmacology of Mescaline and D-Lysergic Acid Diethylamide (LSD)

New England Journal of Medicine January 2, 1958 George B. Koelle 18 citations

Interest in finding a biochemical cause for schizophrenia and other psychoses has recently revived. This is due to modern laboratory techniques that allow detection and measurement of substances in blood and tissues that were previously unmeasurable. The discovery of a partially correctable biochemical defect in phenylketonuria, a type of mental deficiency, has raised hopes that other mental diseases may also have biochemical explanations. Many researchers now think Freudian concepts, which focus on psychological causes, may be insufficient.