THE ELECTROENCEPHALOGRAM AND PSYCHOPATHOLOGICAL MANIFESTATIONS IN SCHIZOPHRENIA AS INFLUENCED BY DRUGS1
Psychosomatic Medicine October 1, 1942 Morton A. Rubin, William Malamud, Justin M. Hope 24 citations
In 14 schizophrenic patients, mescaline, cocaine, sodium amytal, and benzedrine produced changes in personality and brain waves only when psychological changes occurred. Drug effects fell into two categories: those specific to each drug, such as mescaline causing extreme anxiety and a 25 to 30 percent increase in alpha rhythm frequency, and sodium amytal reducing tension while introducing a 15 to 20 per second beta rhythm; and those characteristic of each patient, where psychotic content and reactions to the setting, along with consistent increases or decreases in alpha rhythm percentage, appeared regardless of the drug given.