Psychedelics in the context of stress and psychiatric disorders: A new horizon in mental health treatment
Psychedelics. October 14, 2025 Sha Jin, H.y. Wang, Xiaohui Wang
Stress-related psychiatric disorders like depression, anxiety, and PTSD are widespread and poorly treated. Psychedelics such as psilocybin, LSD, and MDMA are being reconsidered as therapies because they alter consciousness, boost neuroplasticity, and affect emotional processing and serotonin systems. This perspective paper argues that these substances could help treat stress-related conditions and calls for a fundamental shift in how scientists and clinicians understand the link between psychedelics, stress, and mental health.