B-302 Psychedelics and Dissociative Anesthetics: Concentrations in Suspected Impaired Driving Investigations, 2024
Clinical Chemistry October 1, 2025 Stephanie Marco
In 2024, among 328 suspected driving-under-the-influence cases, the most common psychedelic or dissociative drug detected was phencyclidine (PCP, 220 cases), followed by MDMA (81 cases) and ketamine (22 cases). LSD and psilocin were found in only 2 and 5 cases, respectively. Drug concentrations varied widely, with ketamine ranging from 25 to 880 ng/mL, LSD from 3 to 9.8 ng/mL, PCP from 6 to 270 ng/mL, and MDMA from 5.5 to 850 ng/mL. Most drivers also had other central nervous system depressants in their blood. The findings highlight safety concerns for driving as psychedelic therapies become more available.