The case for an integrative model: Hypotheses and rationale for integrative MDMA-Assisted Psychotherapy (IMAP)
Psychedelics January 8, 2026 Rachel Yehuda, Amy Lehrner, Miryam Sperka et al. 2 citations
The original manual for MDMA-assisted therapy (MDMA-AT) for PTSD, developed by the Multidisciplinary Association for Psychedelic Studies (MAPS), introduced concepts like “inner healing intelligence” from transpersonal traditions, which lacked clear grounding in trauma science and were difficult to standardize. In response, a new model called Integrative MDMA-Assisted Psychotherapy (IMAP) is proposed. IMAP is a principle-guided, patient-driven approach rooted in humanistic and trauma-focused psychotherapy. It offers flexible, relationally attuned support for nonlinear therapeutic processes, drawing on contemporary PTSD theories and evidence-based trauma interventions while retaining experiential approaches. The model invites empirical study to determine essential therapeutic elements in psychedelic contexts.