Improved Fischer Indole Reaction for the Preparation of N,N-Dimethyltryptamines: Synthesis of L-695,894, a Potent 5-HT1D Receptor Agonist
The Journal of Organic Chemistry July 1, 1994 Cheng-Yi Chen, Chris H. Senanayake, Timothy J. Bill et al. 150 citations
The Fischer indole reaction was improved to prepare N,N-dimethyltryptamines, enabling the synthesis of L-695,894, a potent 5-HT1D receptor agonist. The new method provides a more efficient route to this class of compounds.