E8‑Based Neurochemical Simulation Accelerates Psilocybin Therapy for Cocaine Addiction — E8 Intelligence Research
Zenodo (CERN European Organization for Nuclear Research) May 29, 2026 Andrew Stewart Caldin
A high-dimensional geometric framework called E8 can encode the coupled dynamics of serotonin-2A receptor activation and dopamine pathways relevant to cocaine addiction. Embedding clinical data on psilocybin and cocaine into this model allows rapid classical simulations that predict therapeutic outcomes, potentially enabling faster optimization of dosing protocols. The original finding suggests that psilocybin could be an effective treatment for cocaine addiction.