Upper Respiratory Infections and Respiratory Adverse Events and Interventions in Emergency Department Sedation of Children.
Annals of emergency medicine April 22, 2025 Daniel S Tsze, Nick Barrowman, Maala Bhatt 1 citation
Children with upper respiratory infections (URIs) undergoing sedation in emergency departments (EDs) do not face a higher risk of respiratory complications or need for serious interventions compared to those without URIs. A secondary analysis of 6,292 children aged 17 years or younger who received parenteral sedation in six pediatric EDs found that the adjusted odds of any respiratory adverse event, serious adverse event, or serious intervention (such as bag-valve-mask ventilation or intubation) were not significantly elevated. The odds ratios were 1.00, 0.53, and 1.08, respectively, with confidence intervals crossing 1.0, indicating no detectable increase in risk.