Partydrogen im Überblick
Psychopharmakotherapie January 1, 2026 Antonia Bendau, Felix Betzler, Twyla Michnevich et al. 1 citation
Party drugs are a diverse group of legal and illegal psychoactive substances used in social settings like clubs and festivals to alter mood, perception, and social interaction. Alcohol and cannabis are most common, followed by amphetamine, MDMA, cocaine, and ketamine. These drugs act through various pharmacological mechanisms: alcohol affects GABAergic, glutamatergic, and dopaminergic systems; cannabis acts on the endocannabinoid system; stimulants increase monoaminergic neurotransmitters; MDMA has a strong serotonergic component; ketamine produces dissociative effects via glutamatergic mechanisms; and psychedelics alter sensory processing through serotonergic modulation. Polydrug use is frequent. Acute risks include cardiovascular strain, hyperthermia, and anxiety, while long-term consequences can involve cognitive impairments, dependence, and social complications.