An analytical study of iboga alkaloids contained in Tabernanthe iboga-derived products offered by ibogaine treatment providers
Archives of Clinical Psychiatry (São Paulo) April 1, 2020 José Carlos Bouso, I. Fornís, Mireia Ventura et al. 15 citations
The purity of iboga products sold online and by treatment providers is highly variable. Analysis of 16 samples—including root bark, total alkaloids, purified total alkaloids, and ibogaine hydrochloride—found ibogaine content ranging from 0.6% to 11.2% in root bark, 8.2% to 32.9% in total alkaloid products, 73.7% in one purified sample, and 61.5% to 73.4% in ibogaine hydrochloride samples. One sample contained no iboga alkaloids. Almost all samples also contained other alkaloids and unknown substances. The variability poses risks for correct dosing and potential adverse reactions or interactions.