Clinical Characteristics of Emergency Visits Related to Recreational Psychedelic Use.
Community mental health journal April 1, 2026 Kush V Bhatt, Joseph Friedman, Lindsay Benster et al.
Recreational psychedelic use is increasing, but data on adverse events is limited. A retrospective chart review of emergency department visits at UC San Diego Medical Center from 2010 to 2023 identified 232 cases linked to LSD (35%), MDMA (30.2%), and psilocybin (24%). Patients were mostly young, white, and male. Common symptoms included agitation (25.9%) and anxiety (24.6%); 11.2% required psychiatric hospitalization. Factors associated with higher odds of hospitalization were concurrent cannabis use (odds ratio 10.9), history of bipolar disorder (odds ratio 12.67), and history of a primary psychotic disorder (odds ratio 17.10). Most psychedelic-related emergency visits are managed without hospitalization, but these specific vulnerabilities predict severe outcomes.