Back to our roots: Integrating wholistic research approaches in the study of medicinal plants and mushrooms
Psychopharmacology April 24, 2026 Melissa L. Perreault, T. Ryan Gregory, Andrew Maxwell Phineas Jones
Whole plants and mushrooms have been used in traditional medicine for millennia, and their use is growing in modern Western societies. Cannabis and psilocybin are prominent examples, driven by greater accessibility, socioeconomic and environmental stress, and evidence of therapeutic value. The medicinal cannabis market was valued at over $21 billion in 2025, projected to reach $116 billion by 2033. The global psychedelic mushroom market is predicted to double to $3.3 billion by 2031, though the medicinal portion is unclear. Other examples include ayahuasca, lion's mane mushrooms, and products used recreationally or for health enhancement.