m-DASC: Measuring Subjective Effects of Very Low Doses of Psychedelic Drugs.
Psychedelic medicine (New Rochelle, N.Y.) March 1, 2026 Jonah Griffin-Stolbach, Hanna Molla, Donald Hedeker et al.
Questionnaires designed for high-dose psychedelic experiences fail to capture the subtle subjective effects of very low doses of LSD. Using data from 199 healthy volunteers given 6.5, 13, and 26 µg doses, a new 31-item questionnaire—the micro-dimensional Altered States of Consciousness (m-DASC)—was developed. It identifies four components: Transcendent Experience, Auditory Somatic Disturbance, Animated Intoxication, and Synesthesia, accounting for 44% of the variance. The m-DASC detected significant effects at 13 and 26 µg and correlated highly with longer questionnaires, offering a more sensitive tool for future low-dose psychedelic research.