Psychedelic-Related Psychosis: From Model Psychosis to Psychotherapy.
Current topics in behavioral neurosciences January 1, 2026 Anna-Lena Bröcker, Tomislav Majić, Christiane Montag 2 citations
Psychotic symptoms are uncommon and non-specific adverse effects of classic psychedelics like LSD, psilocybin, and mescaline. They can occur during the acute drug phase, persist into the subacute period, or rarely develop into long-term psychotic illness. The symptoms can be deeply distressing due to rapid changes, unpredictability, and adverse behavioral consequences. Psychedelics have been used as research models for schizophrenia because of phenomenological overlaps, but this "model psychosis" paradigm has been criticized: etiology and psychodynamic background only partially apply.