2-(4-IODO-2,5-DIMETOXIFENIL)-N-[(2-METOXIFENIL)METIL]ETAMINA OU 25I-NBOME: CARACTERIZAÇÃO QUÍMICA DE UMA DESIGNER DRUG
Química Nova May 9, 2016 Pâmella F. Dos Santos, Lindamara M. Souza, Bianca B. Merlo et al. 13 citations
A new designer drug, 25I-NBOMe, was chemically profiled using multiple analytical techniques. Thin layer chromatography identified spots for 25C-, 25B-, and 25I-NBOMe compounds, all with the same retention factor of about 0.50, but no spots for 2,5-dimethoxy-4-bromoamphetamine, 2,5-dimethoxy-4-chloroamphetamine, or lysergic acid diethylamide. ATR-FTIR preserved the material's physical-chemical properties, while GC-MS and ESI-MS offered better analytical selectivity. ESI(+)FT-ICR MS determined the exact mass (m/z 428.1706 for [M + H]+), molecular formula (C18H22INO3), degree of unsaturation (DBE = 8), and chemical structure via collision-induced dissociation. ATR-FTIR and CID results suggested the presence of isomers, with a second structure proposed as an isomer of 25I-NBOMe.