Editorial Emerging therapeutic opportunities for psychedelic and related drugs
April 1, 2026 Susan Wonnacott, Gary J. Stephens, T. Sharp
Growing interest in psychedelic and related drugs as potential therapies for a wide range of difficult-to-treat conditions, including those beyond neuropsychiatric disorders, has motivated a themed collection of reviews and original articles. The collection covers the mechanistic basis of how these drugs act, the current status of preclinical research and progress in clinical trials, and insight into regulatory processes that determine clinical approval. This editorial introduces these aspects, provides an overview of current controversies and challenges in the field, and highlights the exciting potential these drugs offer.