Growing interest in psychedelic and related drugs as potential therapies for a wide range of difficult-to-treat conditions, including those beyond neuropsychiatric disorders, has motivated a themed collection of reviews and original articles. The collection covers the mechanistic basis of how these drugs act, the current status of preclinical research and progress in clinical trials, and insight into regulatory processes that determine clinical approval. This editorial introduces these aspects, provides an overview of current controversies and challenges in the field, and highlights the exciting potential these drugs offer.
This editorial introduces a themed journal issue on psychedelic and related drugs as potential therapies for a wide range of difficult-to-treat conditions beyond neuropsychiatric disorders. The collection includes reviews and original articles covering the mechanistic basis of how these drugs act, the current status of preclinical research, progress in clinical trials, and insight into regulatory processes for clinical approval. The editorial provides an overview of current controversies and challenges in the field while highlighting the exciting potential these drugs offer.