[Efficacy of psychedelics in psychiatry, a systematic review of the literature].
L'Encephale August 1, 2021 L Berkovitch, B Roméo, L Karila et al. 25 citations
A systematic review of 25 studies found that psychedelics (psilocybin, ayahuasca, and LSD) produce a quick and substantial reduction in symptoms of anxiety, depression, and addiction that lasts for several months, sometimes after a single dose. Studies included randomized controlled trials, open-label trials, and long-term follow-ups, with no severe adverse events reported. However, most studies were descriptive or open-label with small sample sizes. The evidence suggests psychedelics are promising treatments that are well tolerated, but effects need confirmation in larger trials and comparison with standard care.