Ketamine in the Treatment of Depression
Journal of Education Health and Sport February 17, 2025 Urszula Kaczmarska, Michał Jakub Cioch, Julia Nowak et al.
Depression is a common mental illness affecting several percent of adults. This article reviews available knowledge on ketamine as a treatment for depression, covering epidemiology, etiology, side effects, and treatment methods. After over half a century without novel targets for major depressive disorder, ketamine's rapid antidepressant effects in treatment-resistant depression represent a promising breakthrough. The authors conclude that a new era of antidepressant strategies is imminent, and careful analysis of benefits and harms is needed.