Anxiolytic effects of acute and maintenance ketamine, as assessed by the Fear Questionnaire subscales and the Spielberger State Anxiety Rating Scale.
Journal of psychopharmacology (Oxford, England) February 1, 2021 Dylan Truppman Lattie, Hayley Nehoff, Shona Neehoff et al. 13 citations
Ketamine produced rapid, dose-related reductions in fear and anxiety among patients with treatment-resistant anxiety disorders. In a study of 24 patients receiving short-term ascending subcutaneous doses followed by a 3-month maintenance phase, scores on all three Fear Questionnaire subscales (agoraphobia, social phobia, blood-injury phobia) and the Spielberger State Anxiety Inventory decreased quickly after acute dosing and continued to decline progressively during maintenance therapy. Ketamine appears to have broad, dose-related anti-phobic effects, suggesting potential for treating other phobic conditions.