How effective are ketamine or esketamine in treatment-resistant depression?
European Psychiatry November 17, 2023 N. Veluri, Z. Mansuri 1 citation
Ketamine improved treatment-resistant depression symptoms and reduced suicidality by nine-fold and three-fold odds, respectively. Esketamine also improved treatment-resistant depression symptoms. The primary endpoint differed between ketamine (24 hours) and esketamine (28 days). Findings must be interpreted cautiously. Esketamine's effectiveness over 28 days appears promising for treatment-resistant depression.