ChemInform Abstract: Observations Concerning the Synthesis of Tryptamine Homologues and Branched Tryptamine Derivatives via the Borrowing Hydrogen Process: Synthesis of Psilocin, Bufotenin, and Serotonin.
ChemInform July 1, 2016 Silvia Bartolucci, Michele Mari, Giovanni Di Gregorio et al.
A new chemical method for selective indole alkylation uses iridium catalysis and a borrowing hydrogen strategy with amino alcohols as nitrogen-containing electrophiles. The reaction produces alkylated indole products, offering a synthetic route that avoids pre-functionalized starting materials.