Presence of 4-Hydroxy- N -methyl- N -ethyltryptamine in Commercially Available Products
ACS Omega January 7, 2026 Ana Barovic, Monica Pittiglio, Justin Barrett et al.
A tablet sold under the brand name Party Duck and an unlabeled powder were analyzed with nuclear magnetic resonance spectroscopy, gas chromatography/mass spectrometry, and liquid chromatography/mass spectrometry. Both products contained 4-hydroxy-N-methyl-N-ethyltryptamine (4-HO-MET), a synthetic psychedelic similar to psilocin. The tablets held an average of 2.82 or 1.45 mg of 4-HO-MET per tablet, and the powder qualitatively contained the same compound. These results show that 4-HO-MET is present in commercially available products and underscore the need for rigorous analytical methods to monitor tryptamine derivatives in unregulated markets.