Ontogeny of the behavioral effects of lysergic acid diethylamide in cats
Developmental Psychobiology July 1, 1984 Michael E. Trulson, Gailyn A. Howell 5 citations
In cats, the behavioral effects of LSD emerge around 21 days of age and reach adult levels by 35–40 days postpartum. Behaviors such as limb-flicking, abortive grooming, head-shakes, and investigatory responses appear at low frequency before 14 days, then increase rapidly. After an acute injection, effects last about 8 hours from their first appearance. Young kittens (21–42 days old) are resistant to developing tolerance with repeated doses. LSD can elicit behaviors like head-shakes and grooming earlier than they normally appear spontaneously, suggesting the neural and muscular systems for these behaviors develop before natural use.