Distortions of Vision and Pain: Two Functional Facets of D-Lysergic Acid Diethylamide
Perceptual and Motor Skills December 1, 1979 John Michael Williams 2 citations
LSD produces visual distortions and analgesia. Visual effects likely stem from reduced light-evoked input to the dorsal lateral geniculate nucleus from retinal pathways, especially affecting slower or complex-receptive-field afferents. LSD's analgesic effect, accompanied by severe psychotic symptoms, appears to result from actions on a centrifugally controlled pain system involving midbrain raphe neurons.