Psychedelic-assisted psychotherapy: The need to monitor adverse events.
Journal of psychopharmacology (Oxford, England) May 21, 2025 Krj Schruers, N K Leibold
Psychedelic-assisted therapy shows promise for treating mental health conditions, but systematic assessment of adverse events has been neglected. The authors recommend using the term "adverse effects" instead of "side effects" and call for comprehensive monitoring of physical parameters, behavioral outcomes, and subjective experience at baseline and throughout studies. Sex-specific differences should be considered. Several key studies addressing these issues are highlighted. More rigorous adverse effect assessment is needed to ensure safe clinical implementation.