0414 The Interaction of Historical Psychedelic Use and Time Spent in Bed on Sleep Architecture
SLEEP May 1, 2025 April Roper, Chase A. Stratton, Janeese Brownlow
People who have used psychedelic drugs at any point show small differences in objective sleep patterns measured by Fitbit devices compared with non-users. Users averaged 406 minutes in bed and non-users 405 minutes. Psychedelic use predicted more total sleep time, less REM sleep, more light sleep, and more deep sleep, but the effect sizes were negligible. The study analyzed data from 21,076 adults in the All of Us research database, of whom 7,799 reported psychedelic use and 13,277 did not. The findings suggest that while statistically significant differences exist, their practical importance is minimal.