Evaluating Delta-8-THC-Induced Psychosis: A Systematic Review.
Clinical neuropharmacology Megan Jayne Ralston, Alim Osman 1 citation
Delta-8-THC, a cannabinoid gaining popularity, poses significant psychiatric risks including psychosis, mood lability, and cannabinoid hyperemesis syndrome, particularly in individuals with preexisting conditions, despite being less intoxicating than delta-9-THC. A review of six case reports involving 9 patients, mostly males in their 20s with varied psychiatric histories, found that symptoms and clinical outcomes varied. The lack of FDA regulation and easy availability of delta-8-THC products heighten these risks, highlighting the need for more rigorous studies to inform regulatory actions.