Mindfulness for obsessive-compulsive disorder: a systematic review and meta-analysis.
Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) January 1, 2026 Eduardo Aliende Perin, Nelson Carvas, Vinicius Tassoni Civile et al.
A systematic review and meta-analysis of six randomized controlled trials involving 499 adults with obsessive-compulsive disorder (average age 32.8 years, average disorder duration 9.83 years) found that mindfulness-based interventions did not significantly differ from cognitive-behavioral techniques (including exposure with response prevention, psychoeducation, and cognitive restructuring) in reducing obsessive-compulsive symptoms, anxiety, or depression. Dropout rates were similar between groups. A small improvement in mindfulness skills was observed, but it was not clinically relevant. Quality of life findings were inconsistent and could not be pooled. The certainty of evidence ranged from low to high.