Liberation (moksha, nirvana, kaivalya) across Hindu, Buddhist, and Jain traditions is redefined as perpetual self-transcendence through infinite domain expansion, where identity cannot settle in any achieved position. The framework uses mathematical formalization of observable behaviors, comparative analysis of six traditions, and testable criteria including the Liberation Coefficient (LC) and Self-Transcendence Rate (STR). It resolves five traditional controversies by arguing liberation is a process, not a state; involves ego fluidity, not dissolution; requires world engagement; demands all paths simultaneously; and combines sudden recognition with continuous application. This may establish Liberation Science (Liberology) as a measurable behavioral and consciousness phenomenon.
A theoretical model proposes that kundalini, described in yogic literature as a transformative psychophysiological process, may correspond to measurable neurophysiological states of autonomic integration. Preliminary retrospective clinical observations from 404 patients treated for autonomic dysregulation, sleep disturbance, and attentional dysfunction showed patterns of improved heart rate variability, cortisol rhythm restoration, and attentional stability. These patterns followed a four-stage sequence tracked by a proposed neural dispersion index: fragmentation, dormant baseline, progressive integration, and threshold coherence. The model generates four falsifiable predictions but requires formal prospective investigation before clinical conclusions can be drawn.