A scoping review of the effects of serotonergic psychedelics on attitudes towards death.
Psychopharmacology April 21, 2025 Noah N T Barr, Kayla J Giese, Sam G Moreton 1 citation
A systematic review of 31 studies found largely consistent evidence that psychedelic experiences can change attitudes towards death and reduce death anxiety in both clinical and non-clinical populations. However, significant gaps remain in understanding the role of set and setting, differences across psychedelic substances, underlying psychological mechanisms, the potential for worsening death anxiety, and the influence of expectancy and placebo effects. Less is known about the reliability and strength of these effects, the conditions under which they emerge, and which aspects of the experience best predict them.