Analytical Challenges and Health Implications of "Tusi" (2C): A Critical Review.
Critical reviews in analytical chemistry September 12, 2025 Marios C Christodoulou, Agapios Agapiou, Marinos Stylianou 3 citations
Tusi, also known as pink cocaine, is a psychoactive mixture that emerged in Colombia around 2010 and has since spread globally, with notable prevalence in Spain. Despite being mischaracterized as a 2C-class phenethylamine product, it typically contains ketamine, MDMA, amphetamine, methamphetamine, and sometimes cocaine or opioids. In Australia, 133 kg of pink cocaine were seized in 2024, with ketamine purity ranging from 6.8% to 51.3% and MDMA from 15.8% to 33.2%. In the US, the DEA has seized 960 samples since 2020, of which only four contained 2C-B. This critical review details Tusi's composition, health risks, detection methods, and proposes wastewater analysis as a monitoring strategy.