Case report: Improvement in refractory functional seizures, depression, and quality of life with ketamine-assisted therapy
Frontiers in Neuroscience June 12, 2023 E. Argento, Egiroh Omene, Alexandra Jaeger et al. 10 citations
A 51-year-old woman with daily functional seizures, major depressive disorder, and posttraumatic stress disorder who had not responded to prior treatments underwent a novel protocol of ketamine-assisted therapy. After 3 weeks of therapy followed by 20 weeks of intermittent ketamine treatment and ongoing psychotherapy, her seizures were significantly reduced in frequency and severity, and she showed substantial improvements in depressive symptoms and functional ability. This first reported case suggests that ketamine-assisted therapy may help treat functional seizures, but rigorous studies are needed to confirm the findings.