Natural psychedelics in the treatment of depression; a review focusing on neurotransmitters.
Fitoterapia September 1, 2023 Samane Jahanabadi, Shayan Amiri, Mehdi Karkeh-Abadi et al. 14 citations
Natural psychedelic compounds like psilocybin and DMT show promise as novel treatments for depression. This review explains how these substances produce therapeutic effects by interacting with various neurotransmission systems in the brain. It covers current antidepressant strategies and explores the unique mechanisms of natural psychedelics, including DMT, mescaline, ibogaine, and compounds from Amanita mushrooms. The authors describe how these agents may offer alternatives to conventional antidepressants by targeting different neural pathways.