Toxicity of muscimol and ibotenic acid containing mushrooms reported to a regional poison control center from 2002-2016.
Clinical toxicology (Philadelphia, Pa.) February 1, 2019 Michael J Moss, Robert G Hendrickson 41 citations
Ingestion of mushrooms containing ibotenic acid and muscimol often causes gastrointestinal upset, central nervous system excitation, and central nervous system depression, alone or in combination. In a review of 34 cases reported to a US regional poison center from 2002-2016, Amanita pantherina ingestion led to more symptoms than Amanita muscaria: gastrointestinal symptoms in 80% vs. 35%, central nervous system depression in 70% vs. 35%, and central nervous system excitation in 70% vs. 35%. Five patients required intubation; no deaths, seizures, or organ injuries occurred. Among accidental pediatric ingestions, 25% were symptomatic.