Relating movement markers of schizophrenia to self-experience—a mixed-methods study
Frontiers in Psychiatry June 21, 2023 Lily A. L. Martin, David Melchert, Monika Knack et al. 4 citations
Motor abnormalities and basic self-disorders are both considered potential endophenotypes of schizophrenia, but their relationship is rarely studied directly. Using data-driven gait markers previously identified in schizophrenia patients, this work links those movement markers to measures of basic self-disorder from EASE interviews. Quantitative correlations were supported by qualitative content analysis of four patients' interviews. Results indicate an association between movement markers and self-disorders, particularly in cognition, self-experience, and bodily experiences. Although individual movement marker scores did not precisely match patients' descriptions of anomalous self- and body experience, higher marker scores trended with more intense descriptions of specific experiences like hyperreflexivity. The findings support an integrated view of the patient and may inform therapeutic approaches targeting self- and body-experience in schizophrenia.