The effects and toxicity of cathinones from the users' perspectives: A qualitative study.
Human psychopharmacology May 1, 2017 Sulaf Assi, Nargilya Gulyamova, Paul Kneller et al. 35 citations
An analysis of 303 internet discussion forum threads reveals three main themes about cathinone use, effects, and toxicity. Users reported various intake methods depending on the derivative (mephedrone, 3-methylmethcathinone, methylenedioxypyrovalerone) and routes (eyeballing, insufflation, smoking, intravenous, oral, rectal, sublingual), along with multidrug use and purity concerns. Positive effects included increased energy, euphoria, and empathogenic feelings. Toxic effects affected the nervous system (anxiety, hallucinations, nervousness, paranoia), cardiovascular system (angina, myocardial infarction, tachycardia), skin (discolouration, itching, allergy), and renal system (difficulty urinating). Drug-drug interactions with stimulants, depressants, and hallucinogens were also reported. Forums offer useful safety information.