Therapeutic and Structural Dimensions in Psychiatric Prescribing: Bridging Psychedelics and Antidepressants.
Harvard review of psychiatry Christopher W.T. Miller, Zofia Kozak 2 citations
The therapeutic relationship between patient and clinician can significantly shape outcomes of psychotropic medication treatment, including antidepressants and psychedelics. Environmental factors, patient mindsets, and relationship templates influence symptom burden and may amplify or diminish medication effects through placebo or nocebo responses. Some antidepressants heighten neuroplasticity, potentially enhancing the impact of nonmedication factors like the patient-prescriber alliance. Parallels with psychedelics show that preparatory and integrative work with a provider is crucial for outcomes. This paper reviews existing literature on the therapeutic relationship in psychiatric practice, including acute care and psychotropic prescribing.