Francesco Saverio Bersani

2 papers in the library · 139 citations · publishing 2014-2015

Papers

25C-NBOMe: preliminary data on pharmacology, psychoactive effects, and toxicity of a new potent and dangerous hallucinogenic drug

BioMed Research International January 1, 2014 Francesco Saverio Bersani, Ornella Corazza, Gabriella Albano et al. 98 citations

25C-NBOMe, sold online as legal LSD or under names like 'N-bomb' and 'Pandora', is a partial agonist of 5-HT2A receptors that carries a high risk of overdose, with acute toxicity and fatalities reported. It is taken orally, sublingually, nasally, by injection, vaginally, rectally, or smoked, producing effects such as sublingual numbing, stimulation, hallucinations, dissociation, and anxiety. Its use is an emerging phenomenon increased by low-cost online availability, and health professionals should be informed about this trend.

DOI: 10.1155/2014/734749 Full text Synthetic drugs Emerging drugs Novel psychoactive substances Research chemicals +22

Olanzapine as the ideal “trip terminator”? Analysis of online reports relating to antipsychotics' use and misuse following occurrence of novel psychoactive substance‐related psychotic symptoms

Human Psychopharmacology Clinical and Experimental July 1, 2015 Giuseppe Valeriani, Ornella Corazza, Francesco Saverio Bersani et al. 41 citations

People who use novel psychoactive substances (NPS) often self-administer olanzapine to manage psychotic crises or 'bad trips,' a practice facilitated by online sharing of experiences and easy access to medications. Exploratory searches of 163 discussion forums and websites in four languages from November 2012 to 2013 found that olanzapine is the most frequently self-prescribed drug for this purpose, typically taken for a few days at 5–50 mg/day. Only a few formal studies have assessed olanzapine's effectiveness for NPS-induced psychosis, yet pro-drug websites describe it as the 'ideal' molecule to terminate bad trips. Health professionals should be informed about risks of olanzapine misuse.

DOI: 10.1002/hup.2431 Olanzapine Psychiatry Medicine Psychology +1