Application of ORAL{middle dot}screen Saliva Drug Test for the Screening of Methamphetamine, MDMA, and MDEA Incorporated in Hair
Journal of Analytical Toxicology March 1, 2004 A. Miki, M. Katagi, N. Shima et al. 10 citations
A one-step immunoassay drug test originally designed for oral fluid can also screen for methamphetamine, MDMA, and MDEA in hair samples. Extracting a 10-milligram hair specimen with hydrochloric acid and methanol, then reconstituting the extract in water, allows the test to detect these drugs at limits of 0.5 ng/mg for methamphetamine, 0.8 ng/mg for MDMA, and 1.0 ng/mg for MDEA. Results match well with gas chromatography–mass spectrometry confirmation. While positive results require confirmation by a specific alternative method, this approach offers a simple, convenient screening tool for drug enforcement that uses only a small hair sample.