Letter to the editor on "Increased low-frequency brain responses to music after psilocybin therapy for depression".
Journal of affective disorders October 1, 2023 Olivier Brown
A letter to the editor raises methodological concerns about a published study on psilocybin therapy for depression. The original study reported increased low-frequency brain responses to music after treatment, but the letter questions the ANOVA region-of-interest analysis, noting that potential confounds such as age and biological sex may have influenced the reported variance attributed to psilocybin treatment. The letter does not present new data but critiques the statistical approach and suggests the findings may be less robust than claimed.