Improvement in OCD symptoms associated with serotoninergic psychedelics: a retrospective online survey.
Sci Rep August 17, 2023 Anne Buot, Cecile Pallares, Alina Oganesyan et al. 28 citations
Classic psychedelics were the only substances reported to reduce obsessive compulsive disorder (OCD) symptoms in a retrospective online survey of 174 people who used psychoactive drugs. Symptom reduction was linked to the intensity of acute effects, which correlated with dose. Therapeutic effects lasted from weeks to months, but no factor predicted their persistence. Frequency of subsequent use was predicted by the magnitude and persistence of the effect, though overall use was limited. The findings support the possibility that classic psychedelics can reduce OCD symptoms, but careful evaluation of effect persistence is still needed.