Psychedelic Therapeutics for Adolescents: Ethics, Safety, Opportunities, and Equipoise-Authors' Reply.
J Am Acad Child Adolesc Psychiatry December 19, 2024 Jessica K. Jeffrey, Marc J. Weintraub, Charles S. Grob
The authors respond to two letters about their earlier commentary on psychedelic-assisted therapy trials for 16- to 17-year-olds. They reaffirm that ethical and methodologically rigorous research is essential across psychedelic medicine and that conducting such research in adolescents is sensible and worthwhile. They also acknowledge risks from extrapolating adult efficacy data and from off-label prescribing practices common in child and adolescent psychiatry, inviting further dialogue on the subject.