Arylcyclohexylamines (ACHs) are a major group of new psychoactive substances used recreationally and in drug-facilitated sexual assault, with ketamine consumption remaining notably high. This review covers recent laboratory strategies for identifying and quantifying ACH compounds, including phencyclidine, ketamine, and eticyclidine analogues, using traditional analytical techniques and emerging point-of-care sensor technology. The review highlights the consistent need for higher sensitivity in analyzing real-case samples and simulated matrices, and emphasizes ongoing research to develop more sensitive, faster, and more capable sensors.
A new micropump and mass flow sensor design, each smaller than 2 mm per side, can be integrated into a single microfluidic platform for applications such as microdosing. The pump uses electrostatic actuation and active valves, measures 1.86 mm × 1.86 mm × 0.3 mm, and pumps gas at up to 110 μL/min perpendicular to the chip surface. The flow sensor, 1.4 mm × 1.4 mm × 0.4 mm, uses hot-wire anemometry with wires inside a through-hole, enabling direct integration with the pump. First prototypes detect flows around 10 μL/min and measure up to 20 mL/min without dedicated electronics.