Repeated low doses of LSD in healthy adults: A placebo-controlled, dose-response study.
Addict Biol February 1, 2022 Harriet de Wit, Hanna M. Molla, Anya Bershad et al. 82 citations
Repeated low doses of LSD (13 or 26 μg) taken every 3–4 days by healthy adults produced modest subjective effects, such as feeling a drug effect and stimulant-like or LSD-like sensations, but did not improve mood or cognitive performance on psychomotor or most emotional tasks. No lingering effects on mood or task performance were detected at a drug-free follow-up session 3–4 days later. The study concludes that, in a controlled setting with a limited number of administrations, repeated low-dose LSD is safe but yields negligible changes in mood or cognition in healthy volunteers.