Research ethics aspects of experimentation with LSD on human subjects: a historical and ethical review.
Med Health Care Philos June 1, 2019 Kristóf János Bodnár, Péter Kakuk 12 citations
Research with LSD-25 on human participants raises distinct ethical questions that require special attention in study design, conduct, and follow-up. This review of historical and contemporary publications examines the unique ethical issues posed by LSD research, including concerns about participant vulnerability, informed consent, and long-term effects. The authors explore how the substance's powerful psychoactive properties and its controversial history demand careful ethical scrutiny within modern research ethics frameworks. Political and regulatory barriers also affect the clinical and research applications of LSD. The paper argues that these factors together create a need for tailored ethical guidelines beyond standard research protocols.