The therapeutical role of psychedelic drugs in treatment of mental disorders
Bulletin of Integrative Psychiatry September 15, 2021 Dan Cătălin Oprea, Loretta Epure, Vasile Chiriță et al.
Psychedelic drugs, which primarily act on the 5-HT2 serotonergic receptor, are divided into indoleamines (such as LSD, DMT, and psilocybin) and phenethylamines (such as mescaline, DOM, MDA, and MDMA). Historically used in spiritual ceremonies and to treat physical and mental illnesses, research has highlighted their therapeutic potential in psychiatry. Studies on psilocybin and LSD have shown beneficial effects for conditions including anxiety, major depressive disorder, obsessive-compulsive disorder, and addictions to alcohol and smoking.