Exploring new frontiers: Effects of psychedelics on neurotransmitter‐regulated glucagon release in pancreatic islets
Diabetes Obesity and Metabolism December 14, 2023 Mehmet Bostancıklıoğlu
Psychedelic substances like LSD, psilocybin, and DMT may influence glucagon release from pancreatic alpha cells by altering neurotransmitter concentrations involved in intra-islet and extra-islet signaling, an area that remains largely unexplored. This commentary addresses the unprecedented subject of how these substances could affect endocrine activity, particularly neurotransmitter-regulated glucagon release, suggesting a potential link between psychedelics and systemic metabolic functions.